LIMS supports interoperability with other health information systems and equipment via an Application Programming Interface (API). The LIMS APIs is a Representational State Transfer (REST) APIs. The REST API is flexible and is designed to take advantage of existing protocols. When REST APIs are implemented for web applications, it takes advantage of HTTP implying that developers do not need to install additional software or libraries when creating a REST API. The LIMS API is also easily customizable emphasizing extensibility and ease of customization. The following are the LIMS APIs;

1. Authentication : This API allows the user to login to retrieve a user token for subsequent requests
2. Sample Requisition Action: This API is used to send sample data to LIMS
3. Result Request Action : This API is used to request for results from LIMS

4. Result Response Action: This API gives a response once the user requests for results
5. Notifications: This API gives the user the result status of a sample
6. Human Resources: This API is used to fetch  information of lab users from all supported PCR labs
7. Tracking: This API gives the user access to data for equipment monitoring
8. Commodity: This API enables the NDR to pull the CRRF report for